p21 WF1 Ab3 (DCS60.2) 1 ml (0.4 mg/ml)

Product code: MS-230-P; lot 230P1409A, Expiry 9-2016; Product code: MS-230-P0; lot 230P1409C, Expiry 9-2016.

Hematology and Pathology Devices

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Worldwide Distribution: US distribution to states of: CA and WA, and countries of: Serbia, Germany and Netherlands.

Thermo Scientific p21 WF1 Ab-3 (DCS-60.2) || 1 ml (0.4mg/ml): || Product code: MS-230-P and MS-230P0; || Hematology: p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process. || Product is intended for qualitative immunohistochemistry with normal and neoplastic formalin-fixed, paraffin-embedded tissue sections, to be viewed by light microscopy.